Medicine 

Vinelbine 50mg Vinorelbine Injection

Manufacturer

Fresenius Kabi

Active Ingredient 

Vinorelbine 

Storage

Do not freeze; store in a refrigerator (2–8°C).

Consume Type 

Intravenous injection

Description – 

Complete Handbook on Vinelbine 50mg Vinorelbine Injection: Usage and Insight 

Vinelbine 50mg Vinorelbine Injection – Introduction

Vinelbine 50mg Injection is an anti-cancer, chemotherapy medicine that contains Vinorelbine. This injection is used to treat cancers, like, breast cancer, non-small cell lung cancer (NSCLC), and cancer of the outer covering of the lung (mesothelioma).

How Vinelbine 50mg Vinorelbine Injection Works: A Closer Look

Vinelbine 50mg Injection utilizes Vinorelbine, an anti-microtubule agent that inhibits division in tumor/cancer cells, ultimately causing their death. This injection prevents the growth and spread of cancer by disrupting cell division processes critical to their survival. By hampering the ability of cancerous cells to divide, Vinelbine facilitates their eventual destruction, offering a therapeutic approach to combating cancer progression.

Vinelbine 50mg Vinorelbine Injection Use

• Advanced breast cancer
• Non-small cell lung cancer (NSCLC)
• Mesothelioma (cancer of the outer covering of the lung)

Vinelbine 50mg Vinorelbine Injection – The Benefits

Advanced Breast Cancer

Vinelbine 50mg Injection helps treat breast cancer, either on its alone or in combination with other therapies like chemotherapy. By preventing the growth and proliferation of cancer cells, it reduces the signs of breast cancer, including abnormalities in the breast. 

Mesothelioma

Vinelbine 50mg Injection is used for the treatment of Mesothelioma (Cancer of the outer covering of the lung). It is used to prevent and stop the further spread and development of the cancer.

Non-Small Cell Lung Cancer (NSCLC)

Vinelbine 50mg Injection addresses Non-Small Cell Lung Cancer (NSCLC) and can be used either on its own or in conjunction with other drugs. Because of its known toxicity and potency, it must be thoroughly discussed along with the advantages and disadvantages with a healthcare professional. Also, it is recommended to refrain from consuming alcohol while undergoing therapy and to stay well-hydrated by drinking lots of water.

Vinelbine 50mg Vinorelbine Injection – A Usage Guide

One should only get this medicine administered only by an expert medical professional. Do not try to self-administer this med.

Vinelbine 50mg Vinorelbine Injection – Side Effects

Most side effects go away and do not need to be treated once your body adjusts to the medication.  If they continue, or if you are concerned, see your physician.

Common Side Effects

• Burning, numbness, tingling, or painful sensations
• Changes in skin color
• Chest pain
• Chills
• Clay-colored stools
• Constipation
• Cough
• Dark urine
• Decreased appetite
• Dizziness
• Feeling of fullness in the ears
• Fever
• Headache
• Hoarseness
• Itching, skin rash
• Loss of appetite
• Loss of balance
• Loss of hearing
• Lower back or side pain
• Muscle pains, cramps, or stiffness
• Nausea
• Painful or difficult urination
• Pale skin
• Pinpoint red spots on the skin
• Ringing or buzzing in the ears
• Sneezing
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Stomach pain or tenderness
• Swelling of the feet or lower legs
• Swollen glands
• Tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
• Trouble in hearing
• Troubled breathing with exertion
• Unsteadiness or awkwardness
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Yellow eyes or skin
• Black, tarry stools
• Bleeding gums
• Bleeding, blistering, burning, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, tenderness, tingling, ulceration at the injection site
• Blood in the urine or stools
• Bluish color of the skin

[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s specific side effects, refer to the official prescription information or consult your healthcare provider.]

Vinelbine 50mg Vinorelbine Injection – A Guide to Safety 

Alcohol

Combining alcohol and Vinelbine 50mg injection may result in excessive sleepiness, it may be dangerous.

Pregnancy

It is not advised to use Vinelbine 50mg vinorelbine injection while pregnant as it may result in death of fetus and birth defects. Before using this injection, see your doctor if you are pregnant or think you might be.

Breastfeeding

It is probably dangerous to use Vinelbine 50mg vinorelbine injection while nursing a baby. Based on limited human data, the medication may enter breast milk and cause harm to the fetus.

Driving

Do not drive or operate heavy machinery if you are experiencing dizziness, fatigue, sleepiness, or blurred vision. For more advice, please see your physician.

Liver 

Vinelbine 50mg Vinorelbine Injection is probably safe to use in liver disease patients. Based on available data, there is no need to adjust the dosage of Vinelbine 50mg Vinorelbine Injection for these individuals. Please visit your healthcare provider.

Kidney 

For patients with renal illness, Vinelbine 50mg vinorelbine injection is probably safe. According to the available information, it does not seem that these people need to have their dosage of vinelbine 50mg injection changed. Please visit your physician.

Swift Advice

• Inform your doctor about heart, vascular, or bone marrow issues, liver problems, or previous liver radiotherapy.
• Avoid live vaccines and contact with people who have received them during treatment.
• Use dual contraception during and 3 months post-treatment to prevent pregnancy.
• Men should avoid fathering a child during and 3 months after treatment and consider sperm conservation.
• Avoid skin, eye, or mucosa contact due to possible irritation from vinorelbine; wash skin thoroughly if contact occurs.
• Take vinorelbine with a light meal to reduce nausea. Avoid hot fluids with soft capsule gels to prevent quick dissolution.
• Vinelbine 50mg Vinorelbine Injection is not recommended for children under 18 years old.

Frequently Asked Questions – Vinelbine 50mg Vinorelbine Injection

Q1. What is Vinelbine 50mg Vinorelbine Injectionused for?

A:   Vinelbine 50mg Vinorelbine Injection is primarily used in the treatment of various cancers like non-small cell lung cancer and breast cancer. It’s part of a class of medications called vinca alkaloids that work by interfering with the growth of cancer cells.

Q2. How is Vinelbine 50mg Vinorelbine Injection administered?

A:   Typically, Vinorelbine is administered intravenously (IV) by a healthcare professional in a clinic or hospital setting. It’s important to follow the prescribed dosage and administration schedule provided by your doctor.

Q3. What are the potential side effects of Vinelbine 50mg Vinorelbine Injection?

A:   Common side effects may include nausea, vomiting, constipation, fatigue, and hair loss. However, it’s crucial to report any severe side effects like severe allergic reactions, unusual bruising or bleeding, signs of infection, or difficulty breathing to your healthcare provider immediately.

Q4. Can Vinelbine 50mg Vinorelbine Injectioninteract with other medications or conditions?

A:   Yes, Vinelbine 50mg Vinorelbine Injection can interact with various medications, such as

• Itraconazole
• Ketoconazole
• Mavacamten
• Netupitant
• Omaveloxolone
• Phenobarbital
• Certain antibiotics
• Medications that affect the liver

It’s important to inform your healthcare provider about all medications, supplements, and health conditions you have before starting Vinorelbine to avoid potential interactions.

Q5. How often is Vinelbine 50mg Vinorelbine Injection administered?

A: The frequency of Vinorelbine injections can vary based on the type and stage of cancer being treated, as well as individual health factors. Typically, it’s administered once a week or as prescribed by the doctor. Your healthcare provider will determine the appropriate dosage and schedule for your specific condition.