Medicine 

Ibrunat 140mg Ibrutinib Capsules

Manufacturer

Natco Pharma

Active Ingredient 

Ibrutinib

Storage

Store at temperature below 30 °C.

Consume Type 

Capsules

Description – 

Complete Handbook on Ibrunat 140mg Ibrutinib Capsules: Usage and Insight 

Ibrunat 140mg Ibrutinib Capsules – Introduction

Ibrunat 140mg Capsule contains Ibrutinib which is prescribed for the treatment of various blood cancers including mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (CLL), Waldenstrom’s macroglobulinemia, and Marginal zone lymphoma (MZL).

How Ibrunat 140mg Ibrutinib Capsules Works: A Closer Look

Ibrunat 140mg capsules contains Ibrutinib, an antineoplastic drug, which works by inhibiting a particular protein known as Bruton’s tyrosine kinase (BTK), which is essential to the survival and proliferation of cancer cells. Ibrunat 140mg slows down the growth and division of cancer cells by blocking BTK, which ultimately results in the cancer cells’ apoptosis (death).

Ibrunat 140mg Ibrutinib Capsules Use

• Mantle cell lymphoma
• Chronic lymphocytic leukemia (Blood cancer)
• Small lymphocytic lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic graft vs. host disease after failure of systemic therapy

Ibrunat 140mg Ibrutinib Capsules – The Benefits

Mantle Cell Lymphoma:

Ibrunat 140mg Capsules containing Ibrutinib offer significant benefits in treating mantle cell lymphoma. This medication targets specific proteins in cancer cells, inhibiting their growth and spread. It has shown effectiveness in controlling mantle cell lymphoma, a type of aggressive non-Hodgkin lymphoma, by reducing the size of tumors, slowing cancer progression, and enhancing overall survival rates.

Chronic Lymphocytic Leukemia (Blood Cancer):

For chronic lymphocytic leukemia (CLL), a type of blood cancer affecting white blood cells, Ibrunat 140mg Capsules containing Ibrutinib have proven to be a groundbreaking treatment. It works by interfering with the signaling pathways that CLL cells use for survival, thereby impeding their growth and proliferation. This drug has shown remarkable success in improving outcomes for CLL patients, including higher response rates and prolonged periods of remission.

Small Lymphocytic Lymphoma:

Ibrutinib, the active ingredient in Ibrunat 140mg Capsules, has exhibited effectiveness in treating small lymphocytic lymphoma (SLL), which is closely related to CLL. By disrupting the signaling pathways that sustain cancer cells, this medication helps to control the growth and spread of SLL, leading to improved patient outcomes and a higher quality of life.

Waldenstrom’s Macroglobulinemia:

Ibrunat 140 mg  Ibrutinib-containing capsules show promise in treating Waldenstrom’s macroglobulinemia, a rare form of lymphoma marked by aberrant production of antibodies. Ibrutinib targets specific proteins involved in the growth and survival of cancerous cells, leading to a reduction in tumor size, improved blood counts, and a better quality of life for patients with this condition.

Chronic Graft vs. Host Disease After Failure of Systemic Therapy:

Ibrunat 140mg Capsules with Ibrutinib provide hope for patients who have poor response to previous systemic therapies and chronic graft-versus-host disease (GVHD) following allogeneic stem cell transplantation. By controlling immune responses and lowering inflammation, imatinib has demonstrated effectiveness in treating the symptoms of GVHD. This has improved patient outcomes and may open up new treatment options for patients who were not responding to conventional therapies.

Ibrunat 140mg Ibrutinib Capsules – A Usage Guide

Take Ibrunat 140mg at the same time every day. Do not consume grapefruit or orange juice in any form while taking Ibrunat 140mg. Drink plenty of fluids to stay hydrated.

Ibrunat 140mg Ibrutinib Capsules – Side Effects

Most side effects go away and do not need to be treated once your body adjusts to the medication.  If they continue, or if you are concerned, see your physician.

Common Side Effects

• Pneumonia
• Rash
• Diarrhea
• Muscle spasm
• Hemorrhage
• Weight loss
• Low blood platelets
• Fatigue
• Nausea
• Fever
• Anemia (low number of red blood cells)
• Headache
• Peripheral edema
• Stomatitis (Inflammation of the mouth)
• High blood pressure
• Bruising
• Dry eye
• Decreased white blood cell count (neutrophils)
• Musculoskeletal (bone, muscle or joint) pain
• Urinary tract infection
• Second primary malignancies
• Subdural hematoma

[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s specific side effects, refer to the official prescription information or consult your healthcare provider.]

Ibrunat 140mg Ibrutinib Capsules – A Guide to Safety 

Alcohol

Ibrunat 140mg Ibrutinib Capsules and alcohol together may make you extremely sleepy, which could be harmful.

Pregnancy

Using Ibrunat 140mg Ibrutinib Capsules during pregnancy is not advised as it may cause birth defects and the death of the fetus. If you are pregnant or suspect you might be pregnant, consult your doctor before using this injection.

Breastfeeding

Ibrunat 140mg Ibrutinib Capsules use during nursing a newborn is most likely risky. The drug might injure the fetus if it enters breast milk, according to the scant human data.

Driving

If you are feeling lightheaded, exhausted, drowsy, or experiencing blurred vision, do not drive or operate heavy machinery. For more advice, please see your physician.

Liver 

Patients with liver disease can probably safely take Ibrunat 140mg Ibrutinib Capsules. The dosage of Ibrunat 140mg Ibrutinib Capsules for these people does not need to be changed, according to the data that is currently available. Please visit your healthcare provider.

Kidney 

Ibrunat 140mg Ibrutinib capsules are most likely safe for patients with renal disease. According to the available information, it does not appear that these people’s vinelbine 10mg injection dosages need to be changed. Please visit your physician.

Swift Advice

• Immediate medical attention is necessary if you encounter bleeding, infection, difficulty breathing, or chest discomfort.
• Inform your doctor about any history of heart failure or hepatitis infection.
• Avoid taking this medicine before or after surgery as it delays wound healing.
• Consult your healthcare provider for reliable contraception options during treatment and for one month after completing Ibrunat 140mg doses.
• Take the medication consistently at the same time daily, with or without food.
• It’s recommended to maintain hydration and drink ample fluids while on this medication.
• Complete the prescribed course without skipping any dose as directed by your doctor.
• Employ effective birth control methods to prevent pregnancy while using this medication.
• Regular blood tests may be advised by your doctor to monitor liver function and blood cell count.

Frequently Asked Questions – Ibrunat 140mg Ibrutinib Capsules

Q 1. What is Ibrunat 140mg Ibrutinib Capsules, and what conditions does it treat?

A: Ibrunat 140mg Ibrutinib Capsules is a medication used to treat various types of blood cancers, including mantle cell lymphoma, chronic lymphocytic leukemia, small lymphocytic lymphoma, Waldenstrom’s macroglobulinemia, and others.

Q 2. How does Ibrunat 140mg Ibrutinib Capsules work in treating these conditions?

A: Ibrunat 140mg Ibrutinib Capsules works by blocking specific proteins in cancer cells, inhibiting their growth and survival. It targets certain enzymes that are crucial for cancer cell proliferation.

Q 3. What are the common side effects of Ibrunat 140mg Ibrutinib Capsules?

A: Common side effects may include diarrhea, nausea, fatigue, muscle or joint pain, rash, bruising, and anemia. However, side effects can vary from person to person.

Q 4. How should I take Ibrunat 140mg Ibrutinib Capsules?

A: It’s typically taken orally, usually once a day, at the same time each day, with or without food. It’s important not to skip doses and complete the prescribed course as directed by your doctor.

Q 5. Are there any precautions or warnings associated with Ibrunat 140mg Ibrutinib Capsules?

A: Patients should avoid taking Ibrunat 140mg Ibrutinib Capsules before or after surgery due to its potential to delay wound healing. It’s important to inform your doctor about any history of heart failure, hepatitis infection, or if you’re pregnant or planning to become pregnant.

Q 6. Can Ibrunat 140mg Ibrutinib Capsules interact with other medications or supplements?

A: Yes, Ibrunat 140mg Ibrutinib Capsules can interact with certain medications, including blood thinners, antifungal drugs, and certain antibiotics. Always inform your doctor about all medications, supplements, or herbal products you are taking.

Q 7. How often will I need monitoring while taking Ibrunat 140mg Ibrutinib Capsules?

A: Your doctor may recommend regular blood tests to monitor liver function and blood cell count to ensure the medication’s safety and effectiveness.

Q 8. Can I take Ibrunat 140mg Ibrutinib Capsules if I have other medical conditions?

A: It’s crucial to discuss your medical history with your doctor, especially if you have a history of heart problems, liver issues, bleeding disorders, or infections.

Q 9. What should I do if I miss a dose of Ibrunat 140mg Ibrutinib Capsules?

A: If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Q 10. How long does treatment with Ibrunat 140mg Ibrutinib Capsules typically last?

A: The duration of treatment with Ibrunat 140mg Ibrutinib Capsules varies depending on the specific condition being treated and individual patient response. Your doctor will determine the appropriate duration of treatment for you.